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Index > Protein center > Vldlr(Gene name) > Mouse
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  • Vldlr (Gene name),
  • Very low-density lipoprotein receptor (Protein name ),  VLDLR_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Vldlr;
    Protein name:
    Very low-density lipoprotein receptor(VLDL receptor;VLDL-R);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds to the extracellular matrix protein Reelin. Interacts with DAB1. Interacts with VLDLR. Interacts with SNX17.
    Function:
    Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.
    Subcellular Location:
    Membrane Single-pass type I membrane protein Membrane clathrin-coated pit Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    873
    Sequence:
    50:
    MGTSARWALW | LLLALCWAPR | DSGATASGKK | AKCDSSQFQC | TNGRCITLLW | 
    100:
    KCDGDEDCAD | GSDEKNCVKK | TCAESDFVCK | NGQCVPNRWQ | CDGDPDCEDG | 
    150:
    SDESPEQCHM | RTCRINEISC | GARSTQCIPV | SWRCDGENDC | DNGEDEENCG | 
    200:
    NITCSADEFT | CSSGRCVSRN | FVCNGQDDCD | DGSDELDCAP | PTCGAHEFQC | 
    250:
    STSSCIPLSW | VCDDDADCSD | QSDESLEQCG | RQPVIHTKCP | TSEIQCGSGE | 
    300:
    CIHKKWRCDG | DPDCKDGSDE | VNCPSRTCRP | DQFECEDGSC | IHGSRQCNGI | 
    350:
    RDCVDGSDEV | NCKNVNQCLG | PGKFKCRSGE | CIDMSKVCDQ | EQDCRDWSDE | 
    400:
    PLKECHINEC | LVNNGGCSHI | CKDLVIGYEC | DCAAGFELID | RKTCGDIDEC | 
    450:
    QNPGICSQIC | INLKGGYKCE | CSRGYQMDLA | TGVCKAVGKE | PSLIFTNRRD | 
    500:
    IRKIGLERKE | YIQLVEQLRN | TVALDADIAA | QKLFWADLSQ | KAIFSASIDD | 
    550:
    KVGRHFKMID | NVYNPAAIAV | DWVYKTIYWT | DAASKTISVA | TLDGAKRKFL | 
    600:
    FNSDLREPAS | IAVDPLSGFV | YWSDWGEPAK | IEKAGMNGFD | RRPLVTEDIQ | 
    650:
    WPNGITLDLV | KSRLYWLDSK | LHMLSSVDLN | GQDRRIVLKS | LEFLAHPLAL | 
    700:
    TIFEDRVYWI | DGENEAVYGA | NKFTGSELAT | LVNNLNDAQD | IIVYHELVQP | 
    750:
    SGKNWCEDDM | ENGGCEYLCL | PAPQINDHSP | KYTCSCPNGY | NLEENGRECQ | 
    800:
    STSTPVTYSE | TKDINTTDIL | RTSGLVPGGI | NVTTAVSEVS | VPPKGTSAAW | 
    850:
    AILPLLLLVM | AAVGGYLMWR | NWQHKNMKSM | NFDNPVYLKT | TEEDLSIDIG | 
    873:
    RHSASVGHTY | PAISVVSTDD | DLA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse VLDL receptor
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    E1009h
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    ELISA Kit for Mouse VLDL receptor
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    E1009m
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    96T
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    ELISA Kit for Mouse VLDL receptor
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    E1009r
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    96T
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    ELISA Kit for Mouse VLDL receptor
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    ELISA Kit for Mouse VLDL receptor
    Cat.:
    E1009c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse VLDL receptor
    Cat.:
    U1009c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse VLDL receptor
    Cat.:
    U1009r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse VLDL receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse VLDL receptor
    Cat.:
    U1009m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse VLDL receptor
    Cat.:
    U1009h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse VLDL receptor
    Cat.:
    P1009Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse VLDL receptor
    Cat.:
    P1009Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse VLDL receptor
    Polyclonal Antibody for Mouse VLDL receptor
    Polyclonal Antibody for Mouse VLDL receptor
    Cat.:
    P1009Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse VLDL receptor
    Monoclonal Antibody for Mouse VLDL receptor
    Monoclonal Antibody for Mouse VLDL receptor
    Monoclonal Antibody for Mouse VLDL receptor
    Monoclonal Antibody for Mouse VLDL receptor
    Protein for Mouse VLDL receptor
    Protein for Mouse VLDL receptor
    Protein for Mouse VLDL receptor
    Protein for Mouse VLDL receptor
    Protein for Mouse VLDL receptor

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mouse very-low-density-lipoprotein receptor (VLDLR) cDNA cloning, tissue-specific expression and evolutionary relationship with the low-density-lipoprotein receptor."
      Oka K. , Ishimura-Oka K. , Chu M.J. , Sullivan M. , Krushkal J. , Li W.H. , Chan L.
      Eur. J. Biochem.224:975-982(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Heart.
    2. 2.
      "Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19."
      Gafvels M.E. , Paavola L.G. , Boyd C.O. , Nolan P.M. , Wittmaack F. , Chawla A. , Lazar M.A. , Bucan M. , Angelin B.O. , Strauss J.F.
      Endocrinology135:387-394(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Skeletal muscle.
    3. 3.
      "The mouse very low density lipoprotein receptor (Vldlr) gene maps to chromosome 19."
      Naggert J.K. , Mu J.L.
      Mamm. Genome5:453-455(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 204-262
    4. 4.
      "Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation."
      Hiesberger T. , Trommsdorff M. , Howell B.W. , Goffinet A.M. , Mumby M.C. , Cooper J.A. , Herz J.
      Neuron24:481-489(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH REELIN
    5. 5.
      "The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor."
      Stockinger W. , Sailler B. , Strasser V. , Recheis B. , Fasching D. , Kahr L. , Schneider W.J. , Nimpf J.
      EMBO J.21:4259-4267(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SNX17
    6. 6.
      "Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia."
      Jones C. , Hammer R.E. , Li W.-P. , Cohen J.C. , Hobbs H.H. , Herz J.
      J. Biol. Chem.278:29024-29030(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LDLRAP1
    7. 7.
      "The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2."
      Hong C. , Duit S. , Jalonen P. , Out R. , Scheer L. , Sorrentino V. , Boyadjian R. , Rodenburg K.W. , Foley E. , Korhonen L. , Lindholm D. , Nimpf J. , van Berkel T.J. , Tontonoz P. , Zelcer N.
      J. Biol. Chem.285:19720-19726(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION
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